What is confirmed
Shoggoth is the first full boss encounter. Activate the three devices in its arena to expose its eyes, then damage the exposed eyes before repeating the cycle. Slither Prime is the final boss: its head is the weak point, while summoned enemies and its own attacks create the pressure. Xbox also identifies the Acheronian Juggernaut as a powerful mini-boss-tier threat rather than a full boss encounter.
What to do
Save at the last safe room, carry healing and ammunition for several weapons, then learn the arena before committing to a long reload. Against Shoggoth, prioritize the devices and use the openings to shoot its eyes. Against Slither Prime, keep moving to avoid attacks, clear summoned enemies when they obstruct the arena, and return fire to the head whenever the line is open.
What is not confirmed
Boss names, locations and tactics are story spoilers. This page deliberately omits cinematic context, health values and unverified phase counts. Difficulty, patch changes and your available weapons can alter how much ammunition each encounter needs, so do not treat a fixed loadout as mandatory.
Player questions
Who is the final boss in The Sinking City 2?
Slither Prime is the final boss. Focus damage on its head, stay mobile to avoid its attacks, and deal with summoned enemies before they overwhelm the arena.